Vice Ganda has done it again—setting social media ablaze with another iconic one-liner that sent fans into uncontrollable laughter. This time, the punchline came during a spontaneous moment that involved none other than popular content creator Esnyr Ranollo, and the internet can’t stop talking about it.

In a recent episode of It’s Showtime, Vice was in peak comedic form, interacting with audience members and guests in the kind of witty, off-the-cuff banter that has made her a household name. While hyping up a contestant or co-host (as is tradition on the show), Vice quipped, “Pag ‘di ka nag-enjoy, ako back-up?!”—a hilarious line suggesting that if things don’t go well, Vice would have to be the fallback option.

The line on its own was already gold—but it didn’t stop there.

Mid-joke, Vice turned to the crowd and pulled Esnyr Ranollo into the scene. “Nadamay pa si Esnyr! HAHAHAHA!” she added, sparking even more laughter from the studio audience and prompting a flood of reactions online. Esnyr, known for his viral skits and relatable Gen Z humor, played along, instantly making the moment even more unforgettable.

Clips of the exchange quickly made their way across Facebook, TikTok, and X (formerly Twitter), gaining hundreds of thousands of views within hours. Fans praised Vice for her perfect comedic timing and Esnyr for his naturally funny reactions. Many commented on how these unscripted moments are exactly what keep It’s Showtime so fresh and entertaining after all these years.

One comment perfectly captured the sentiment: “Walang kupas si Meme Vice! Pati si Esnyr napasama sa katatawanan!”

Others were quick to meme the moment, pairing it with everyday situations like group projects or awkward dates: “Pag ‘di ka natawa sa joke ng crush mo, ako ba magba-back-up?”

The chemistry between Vice and Esnyr also sparked hopes from fans for a future collab, with many saying their combined comedic energy is “too powerful” to ignore.

What makes this viral moment hit so hard is its authenticity. Vice has always had a talent for bringing people into the joke—never to insult, always to connect. That spontaneous charm, combined with Esnyr’s naturally expressive reactions, turned a random studio moment into pure entertainment gold.

In a time when so much of our online content is polished and curated, it’s the raw, real, and genuinely funny moments like these that remind us why live TV still has magic. No script, no special effects—just two icons, one stage, and a line that now lives rent-free in everyone’s heads.